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General information

Location
Cambridge, MA
Ref #
43799
Job Family
Research
Workplace
On-Site
Date published
03/02/2026
Time Type
Full time
Pay Range
$115,000.00/yr - $161,667.00/yr

Description & Requirements

The Broad Institute of MIT & Harvard is seeking an outstanding and innovative Senior Computational Scientist to join the Methods Development Lab.


The Senior Computational Scientist is responsible for driving the computational development of novel -omic technologies generated at the Methods Development Lab. The Senior Computational Scientist will lead computational efforts of collaborative projects with Broad Programs and Platforms, with an emphasis on Cell Circuits, the Klarman Cell Observatory, Gene Regulation Observatory, Immunology Program, Data Sciences Platform, and Genetic Perturbation Platform. In addition, the Senior Computational Scientist will keep current with the state of the field and interests/needs of Broad researchers and work with the Methods Development Lab Group Leader to conceptualize, prioritize, and then develop new methods. The Senior Computational Scientist will work closely with Genomics Platform R&D, Automation, LIMS, production teams, and Data Sciences Platform to translate novel methods into production scale processes to make them available to the community.

RESPONSIBILITIES

  • Design and drive novel technology development projects within specific areas as agreed upon with the MDL Group Leader. 
  • Manage computational biologists working on MDL projects.
  • Work closely with GP and DSP computational biologists/scientists to create analytic methods for novel technologies and novel resources for the community. 
  • Help evaluate new -omic technologies to determine utility, impact, fit with Genomics Platforms capabilities and interests.
  • Assists and actively participates in obtaining federal, philanthropic, institutional, or industrial funding opportunities for technology development.
  • Publish novel methods in collaboration with Broad scientists. 
  • Seek intellectual property protection for inventions that are conceived of or developed while a member of the MDL. 
  • Provides input on strategic guidance with the Group Leader 
  • In coordination with the Group Leader, set priorities and goals on the development of new methods, timeline, and budget. 

SKILLS AND ABILITIES
  • Must be passionate and deeply committed to the mission of the Methods Development Lab and the entire Broad.  
  • Must be forward-thinking and innovative, with a nimble scientific/technical mind, able to rapidly develop and execute on creative solutions.
  • Must be skilled at supervising teams of researchers, providing both scientific mentorship and direction. 
  • Must be proficient in setting goals, priorities, and budgets to drive efficient project execution. 
  • Must have deep computational biology experience.
  • Must have excellent programming skills, data analysis skills, and a mastery of best software practices.
  • Strong individual contributor with the ability to quickly pivot and collaborate with key stakeholders and senior leadership 

QUALIFICATIONS
  • PhD degree in Computational Biology or related field with 5+ years of experience

The expected base pay range for this position as listed above is based on a 40 hour per week schedule. Broad provides pay ranges representing its reasonable and good faith estimate of what the organization reasonably expects to pay for a position at the time of posting. Actual compensation will vary based on factors including but not limited to, relevant skills, experience, education, qualifications, and other factors permissible by law.
 
At Broad, your base pay is just one part of a comprehensive total rewards package. From day one, this role offers a competitive benefits package including medical, dental, vision, life, and disability insurance; a 401(k) retirement plan; flexible spending and health savings accounts; at least 13 paid holidays; winter closure; paid time off; parental and family care leave; and an employee assistance program, among other Broad benefits.

The Broad Institute is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, disability, protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations.

Should you need a reasonable accommodation to complete the application or interview process, please contact recruiting@broadinstitute.org for assistance.