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General information

Location
Cambridge, MA
Ref #
44073
Job Family
Research
Workplace
On-Site
Date published
04/24/2026
Time Type
Full time
Pay Range
$70,000.00/yr - $92,666.67/yr

Description & Requirements

We are seeking a highly motivated Postdoctoral Associate to join an interdisciplinary research team at the Broad Institute, working at the interface of biomaterials, drug delivery, and cell-based therapeutics. The position is embedded within a collaborative environment spanning the Broad Institute, MIT, and affiliated hospitals, with a strong emphasis on translational science and clinically impactful technologies.


Research Focus


The successful candidate will lead and contribute to projects focused on:


  • Macro-encapsulation systems for cell therapies, including hydrogel-based and implantable platforms
  • Design and synthesis of novel polymers for the delivery of nucleic acids (e.g., mRNA, DNA)
  • Development of polymer-lipid hybrid nanoparticles and advanced biomaterials
  • Integration of delivery systems into implantable or ingestible devices
  • Preclinical evaluation of therapeutic systems in relevant in vivo models
  • This work builds on ongoing efforts in cell therapy, gene delivery, and next-generation biomaterials platforms

Key Responsibilities

  • Design and synthesize novel polymeric materials for nucleic acid delivery
  • Develop macro-encapsulation platforms for cell-based therapies
  • Conduct in vivo studies in rodent models (e.g., biodistribution, efficacy, safety)
  • Perform in vitro characterization, including cell culture, 3D models, and mechanistic studies
  • Collaborate across disciplines, including engineering, biology, and clinical teams
  • Contribute to high-impact publications, grant writing, and translation efforts


Required Qualifications


  • 0+ years of post-graduate experience
  • PhD in Biomedical Engineering, Pharmaceutical Sciences, Materials Science, or related field
  • Strong background in drug delivery, biomaterials, or nanomedicine
  • Demonstrated expertise in:
    • Polymer synthesis and characterization
    • Nucleic acid delivery systems (e.g., LNPs, polymeric carriers)
    • Cell encapsulation or hydrogel systems
  • Hands-on experience with in vivo rodent models, including study design and execution
  • Track record of peer-reviewed publications


Preferred Qualifications


  • Experience with macro-encapsulation or implantable devices for cell therapy
  • Familiarity with mRNA delivery, vaccines, or gene therapy platforms
  • Experience with advanced imaging, biodistribution, or disease models (e.g., cancer, CNS)
  • Exposure to translational research or industry collaborations

Why Join

  • Work at the cutting edge of biomaterials and therapeutic delivery
  • Access to world-class resources across the Broad Institute, MIT, and Harvard
  • Highly collaborative, fast-paced environment with strong emphasis on real-world impact
  • Opportunities for career development, mentorship, and entrepreneurship

The expected base pay range for this position as listed above is based on a 40 hour per week schedule. Broad provides pay ranges representing its reasonable and good faith estimate of what the organization reasonably expects to pay for a position at the time of posting. Actual compensation will vary based on factors including but not limited to, relevant skills, experience, education, qualifications, and other factors permissible by law.
 
At Broad, your base pay is just one part of a comprehensive total rewards package. From day one, this role offers a competitive benefits package including medical, dental, vision, life, and disability insurance; a 401(k) retirement plan; flexible spending and health savings accounts; at least 13 paid holidays; winter closure; paid time off; parental and family care leave; and an employee assistance program, among other Broad benefits.

The Broad Institute is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, disability, protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations.

Should you need a reasonable accommodation to complete the application or interview process, please contact recruiting@broadinstitute.org for assistance.