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General information

Location
Cambridge, MA
Ref #
41929
Job Family
Research
Workplace
On-Site
Date published
07-Mar-2025
Time Type
Full time

Description & Requirements

The Broad Institute of MIT and Harvard is seeking an outstanding Postdoctoral Associate candidate to join the Priming Agent Team—an exciting multidisciplinary and multi-lab collaboration led by Viktor Adalsteinsson (Gerstner Center for Cancer Diagnostics at Broad), Sangeeta Bhatia (MIT), and J. Christopher Love (MIT)—that seeks to unlock the power of liquid biopsies for cancer diagnostics, by addressing critical biological bottlenecks.

The goal of the Priming Agent Team is to develop the first diagnostic drugs for liquid biopsies that improve the recovery of circulating tumor DNA (ctDNA) to enable early cancer detection, monitoring for minimal residual disease, and minimally-invasive tumor genotyping from blood samples (see Martin-Alonso et al Science 2024).

We are seeking an exceptionally motivated individual to pursue next generation strategies involving protein engineering, nanoparticle engineering, drug delivery, and/or synthetic biology approaches, to further elucidate the biology of tumor DNA release and clearance from circulation and to improve how it is sampled from the body.

Our team includes scientists, engineers, medical oncologists, and computational biologists, spanning the Broad Institute, MIT, Harvard, and Harvard-affiliated hospitals, and the successful candidate will gain exposure to cutting-edge science through meetings, symposia, and interactions with colleagues and collaborators.

QUALIFICATIONS
  • Ph.D. in Bioengineering or related field required.
  • Deep biological understanding and technical skills.
  • Exceptionally innovative and rigorous in problem-solving.
  • Proven track record in scientific research and publications.
  • Thrives in a fast-paced environment and enjoys collaborating with others.
  • Strong interpersonal, organizational, communication, and leadership skills.
  • Experience with mouse models is preferred.