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General information

Location
Cambridge, MA
Ref #
5299
Job Family
Research
Workplace
On-Site
Date published
24-Jul-2024
Time Type
Full time

Description & Requirements

The Broad

The Broad Institute of MIT and Harvard is one of the world's leading biomedical research institutes. It seeks to discover the molecular basis of major human diseases, develop effective new approaches to diagnostics and therapeutics, and disseminate discoveries, tools, methods, and data openly to the entire scientific community. Founded in 2004, the Broad Institute includes faculty, professional staff, and students from throughout the MIT and Harvard biomedical research communities, with collaborations spanning the globe. 


Group Description

 Research in Stanley Center at Broad Institute aims to reveal the genetic, molecular, cellular and circuitry underpinnings of psychiatric disorders, and eventually to develop novel effective treatments. A postdoctoral position is available to study the brain development, synapse/neural circuit function and neurobiological mechanisms underlying psychiatric disorders. Brief Summary We seek candidates who are interested in decoding the biological causes of psychiatric diseases, such as schizophrenia, autism and bipolar disorders. The successful candidate will join an interdisciplinary team at the Stanley Center for Psychiatric Research. 

Job Responsibilities

Individuals with excellent past record of research achievement in electrophysiology, in particular synaptic and circuitry physiology studies, are encouraged to apply. The candidates are expected to perform in vitro and in vivo electrophysiological studies using multiple models ranging from in iPSCs/ES-based cells, 3D brain organoids, acute brain slices to in vivo extracellular multi-electrodes recordings . Excellent technical optimization and problem-solving skills will be required. Experience with optical electrophysiology, behavioral tests, and programming (MATLAB) is a plus. Key

  •  Implement and develop in vitro and in vivo electrophysiological protocols and assays 
  • Interact and coordinate with collaborators as required 
  • Publish scholarly reports and present at scientific conferences 
  • Participate within a team of scientists to foster a culture of scientific discourse and    excellence 
  • Other related tasks as need 

Minimum Qualifications

  • Ph.D. in Neuroscience, Neurobiology, Cell biology or related field. Prior postdoctoral experience in not an essential. 
  • Demonstrated technical proficiency in electrophysiological techniques (such as whole-cell patch clamp recordings, extracellular field potential recordings and single unit or multi-unit recordings). 
  • Embracing technical challenges and having excellent capability of trouble shooting. 
  • Outstanding personal initiative and communication skills.  
  • Must work well in a team environment.