Description & Requirements
The Broad Institute of MIT and Harvard is dedicated to transforming medicine by dramatically accelerating the understanding and treatment of disease. The Institute fosters a vibrant and collaborative research environment that bridges disciplines and institutions, including close ties with Harvard, MIT, and the Harvard hospitals.
About the Biology of Adversity Project (BAP)
The Biology of Adversity Project (BAP) is a collaborative initiative at the Broad Institute focused on uncovering how adversity (e.g. fear, deprivation, enrichment) leaves molecular imprints on the genome that shape health and disease. BAP is funded through a generous donation and uses these resources to bring together experts in neuroscience, developmental biology, immunology, genomic technologies, and computational biology to study these molecular records across tissues and at scale.
Position Overview
We are seeking an exceptional Postdoctoral Associate to join the Buenrostro Lab as part of the Biology of Adversity Project. The fellow will reveal mechanisms that connect life experience and environmental stressors with molecular and cellular dysfunction. To pursue this work, the candidate will have access to cutting-edge single-cell and spatial genomic technologies, as well as opportunities for co-mentorship and collaboration across BAP-affiliated labs spanning diverse biological disciplines.
Key Responsibilities
- Lead independent and collaborative research into the molecular mechanisms by which adversity influences the healthy functions of cells
- Apply and develop advanced molecular, single-cell, and spatial genomics techniques
- Integrate findings across tissues and systems in collaboration with affiliate labs in neuroscience, immunology, developmental biology, and genomic technologies
- Present results in internal meetings and external conferences; contribute to manuscripts and grant proposals
Qualifications
- 0+ years of post-grad experience
- Ph.D. in Molecular Biology, Neuroscience, Developmental Biology, Cell Biology, Immunology, or a related field
- Experience with genomics preferred
- Demonstrated creativity, independence, and collaborative spirit
Environment and Mentorship
The fellow will be primarily situated in the Buenrostro Lab, with access to BAP’s collaborative network of affiliated labs. This position offers an exceptional training environment, with opportunities to leverage innovative technologies, work across labs that specialize in developmental biology, immunology, and neuroscience, to create an integrated understanding of the organismal impact of adversity and its association with disease.