Broad Institute

Job Description

The Blainey lab is seeking an exceptional postdoctoral associate to contribute to the technical development and deployment of optical pooled screening (OPS) technology.  This postdoc will join a collaborative team of scientists and engineers to apply our lab’s OPS platform for the discovery of potentially targetable molecular pathways relevant to disease genes and variants. This work entails deep engagement with teams across the Broad Institute. 

This individual will have a background in microscopy, cell biology, genetics, molecular biology, and have some expertise in computational or statistical data analysis.  The individual will lead technology development and project design/implementation/interpretation as fitting their expertise and needs across our teams. 

The Broad Institute of MIT and Harvard is the world's leading biomedical research institute dedicated to the bold mission of using the full power of genomics to transform the understanding and treatment of disease. We seek to describe all of the molecular components of life and their connections; discover the molecular basis of major human diseases; develop effective new approaches to diagnostics and therapeutics; and disseminate discoveries, tools, methods, and data openly to the entire scientific community.

Qualifications

• Ph.D. in a life science field such as biological engineering, biophysics, biochemistry, genomics, immunology, neuroscience, molecular or cell biology or equivalent experience required

Required skills and experience: 

• Self-motivated and curious experimentalist with strong project-level orientation and commitment
• Ability to design and interpret complex experiments involving cells, genome editing, nucleic acid analysis and imaging
• Collaborative team-oriented mindset and ability to share both workload and credit
• Ability to work coordinately in a dynamic interdisciplinary and inter-institutional environment 
• Demonstrated ability to think creatively to solve problems independently and with others
• Strong writing skills, as evidenced by a strong record of publication as a major contributor across a variety of settings, are particularly valued
• Outstanding organization and time management with attention to detail
• Statistical analysis and interpretation of complex large-scale datasets 
• Cell culture, automated microscopy (Nikon Elements), molecular assay design skills and experience
• Experience with optical system design
• Experience with automation for liquid handling

The Broad Institute provides a vibrant research environment with close links to top academic institutions across the Boston Area and provides the potential for the associate's contributions to be used and recognized worldwide.